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Jonathan G Drachman Selected Research

dacetuzumab

1/2015Dacetuzumab plus rituximab, ifosfamide, carboplatin and etoposide as salvage therapy for patients with diffuse large B-cell lymphoma relapsing after rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone: a randomized, double-blind, placebo-controlled phase 2b trial.
6/2014A phase II study of dacetuzumab (SGN-40) in patients with relapsed diffuse large B-cell lymphoma (DLBCL) and correlative analyses of patient-specific factors.
2/2013Pilot study of dacetuzumab in combination with rituximab and gemcitabine for relapsed or refractory diffuse large B-cell lymphoma.
5/2010A phase I multidose study of dacetuzumab (SGN-40; humanized anti-CD40 monoclonal antibody) in patients with multiple myeloma.
2/2010A phase I study of dacetuzumab (SGN-40, a humanized anti-CD40 monoclonal antibody) in patients with chronic lymphocytic leukemia.
9/2009Phase I study of the humanized anti-CD40 monoclonal antibody dacetuzumab in refractory or recurrent non-Hodgkin's lymphoma.

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Jonathan G Drachman Research Topics

Disease

6Neoplasms (Cancer)
06/2014 - 06/2005
4Thrombocytopenia (Thrombopenia)
08/2009 - 01/2004
3Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
01/2015 - 02/2013
2Non-Hodgkin Lymphoma (Lymphosarcoma)
02/2013 - 09/2009
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2009 - 06/2005
1Infections
01/2015
1Cytopenia
01/2015
1Cough
01/2015
1Lymphoma (Lymphomas)
06/2014
1Multiple Myeloma
05/2010
1Inflammation (Inflammations)
05/2010
1Cytokine Release Syndrome
05/2010
1B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
02/2010
1Conjunctivitis
09/2009
1Chills
08/2009
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2006
1Polyploidy
07/2005
1Hemorrhage
07/2005
1Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2004
1Purpura
01/2004
1Thrombocytopenia 1
02/2003
1Wiskott-Aldrich Syndrome
02/2003

Drug/Important Bio-Agent (IBA)

6dacetuzumabIBA
01/2015 - 09/2009
4Monoclonal AntibodiesIBA
06/2014 - 09/2009
2Rituximab (Mabthera)FDA Link
01/2015 - 02/2013
2Immunoconjugates (Immunoconjugate)IBA
01/2013 - 10/2006
1IfosfamideFDA LinkGeneric
01/2015
1Carboplatin (JM8)FDA LinkGeneric
01/2015
1Vincristine (Oncovin)FDA LinkGeneric
01/2015
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2015
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2015
1Prednisolone (Predate)FDA LinkGeneric
01/2015
1Etoposide (VP 16)FDA LinkGeneric
01/2015
1Immunoglobulin G (IgG)IBA
06/2014
1GemcitabineFDA Link
02/2013
1AntibodiesIBA
01/2013
1EnzymesIBA
05/2010
1SteroidsIBA
05/2010
1Serine (L-Serine)FDA Link
08/2009
1lintuzumabIBA
08/2009
1Messenger RNA (mRNA)IBA
08/2009
1Threonine (L-Threonine)FDA Link
08/2009
1Phosphotransferases (Kinase)IBA
08/2009
1Docetaxel (Taxotere)FDA Link
10/2006
1SU 6656IBA
07/2005
1Thrombopoietin (c-mpl Ligand)IBA
07/2005
1Transcription Factors (Transcription Factor)IBA
06/2005
1Inosine Triphosphate (ITP)IBA
01/2004
1Proteins (Proteins, Gene)FDA Link
02/2003

Therapy/Procedure

4Therapeutics
01/2013 - 07/2005
1Salvage Therapy
01/2015
1Immunotherapy
06/2014
1Drug Therapy (Chemotherapy)
10/2006
1Splenectomy
08/2004